Facilitated Assessment of Tissue Loss Following Traumatic Brain Injury

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چکیده

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Facilitated Assessment of Tissue Loss Following Traumatic Brain Injury

All experimental models of traumatic brain injury (TBI) result in a progressive loss of brain tissue. The extent of tissue loss reflects the injury severity and can be measured to evaluate the potential neuroprotective effect of experimental treatments. Quantitation of tissue volumes is commonly performed using evenly spaced brain sections stained using routine histochemical methods and digital...

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Objective(s) Cytokines such as IL-1β are involved in inflammatory responses. This study evaluated the role of two different kinds of drugs (ibuprofen and celecoxib) on brain IL-10 and IL-1β after traumatic brain injury (TBI) in male rats. Materials and Methods Rats were assigned into 6 groups: intact, sham, TBI, and treated rats with vehicle, celecoxib or iboprophen. Cytokine concentrations ...

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P22: Traumatic Brain Injury

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Hypersomnia following traumatic brain injury.

STUDY OBJECTIVES To evaluate the prevalence and natural history of sleepiness following traumatic brain injury. METHODS This prospective cohort study used the Sickness Impact Profile to evaluate sleepiness in 514 consecutive subjects with traumatic brain injury (TBI), 132 non-cranial trauma controls, and 102 trauma-free controls 1 month and 1 year after injury. RESULTS Fifty-five percent of...

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ژورنال

عنوان ژورنال: Frontiers in Neurology

سال: 2012

ISSN: 1664-2295

DOI: 10.3389/fneur.2012.00029